Hippocampal neural stem cells and microglia response to experimental inflammatory bowel disease (IBD)

Treatment of inflammatory bowel disease (IBD).

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract, which includes Crohn's disease (CD) and ulcerative colitis (UC). These diseases have become important health problems. Medical therapy for IBD has advanced dramatically in the last decade with the introduction of targeted biologic therapies, the optimization of older therapies, including rugs such ...

Digestive System Inflammatory Bowel Disease (IBD)

Inflammatory bowel disease is an immune related disorder in which the intestines are chronically or intermittently inflamed. A synonym for inflammatory bowel disease that is abbreviated the same way is ‘irritable bowel disease’. Affected dogs may be presented with a history of vomiting, diarrhea, weight loss or a combination of these signs. There is a great deal of variation in the severity, du...

Evaluation of Antibody Response to Polysaccharide Vaccine and Switched Memory B Cells in Pediatric Patients with Inflammatory Bowel Disease

Background/Aims: Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract, whose etiologies are still unknown. This study was performed to evaluate the humoral immune response in terms of B cell functions in selected IBD patients. Methods: Eighteen pediatric patients with IBD, including 12 cases of ulcerative colitis (UC) and six with Crohn disease (CD), were enrolled...

Endoscopy in Paediatric Inflammatory Bowel Disease (IBD)

Know Your Variability: Challenges in Mechanistic Modeling of Inflammatory Response in Inflammatory Bowel Disease (IBD)